Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELP | P16109 | 4/20 | 0.47 |
| ▸ | SELL | P14151 | 3/20 | 0.47 |
| ▸ | SELE | P16581 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7430649 | 0.89 | SELL (0.56) | SELPSELLSELELTB4RGAA | |
| SCHEMBL7430609 | 0.88 | NPC1 (0.46) | SELPSELLSELELTB4RMEN1 | |
| SCHEMBL7429346 | 0.87 | SELL (0.45) | SELPSELLSELEMAPK1LTB4R | |
| SCHEMBL7433940 | 0.86 | LTB4R (0.62) | LTB4RHDAC1AKR1C3AKR1C2MEN1 | |
| SCHEMBL7439374 | 0.83 | KMT2A (0.44) | MAPK1GAAGFERMEN1LMNA | |
| SCHEMBL7438717 | 0.82 | ALOX15 (0.50) | SELPSELLSELEALOX15MAPK1 | |
| SCHEMBL7435487 | 0.82 | HDAC3 (0.49) | HDAC1GAA | |
| SCHEMBL7427426 | 0.82 | LTB4R (0.39) | SELPSELLSELELTB4RHIF1A | |
| SCHEMBL7432442 | 0.82 | L3MBTL1 (0.44) | MAPK1GAAKDM4EMEN1LMNA | |
| SCHEMBL7432797 | 0.82 | SMN1; SMN2 (0.51) | HDAC1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |