Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | BMP1 | P13497 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7432264 | 0.90 | F2 (0.36) | F2PRSS1PLGRIPK1BMP1 | |
| SCHEMBL7438271 | 0.86 | F2 (0.43) | F2PRSS1PLGRIPK1OPRK1 | |
| SCHEMBL7433686 | 0.85 | F2 (0.46) | F2PRSS1PLGRIPK1OPRK1 | |
| SCHEMBL7441617 | 0.82 | CA2 (0.36) | F2PRSS1PLGCA1CA2 | |
| SCHEMBL7441705 | 0.81 | CA2 (0.35) | F2PRSS1PLGCA1CA2 | |
| SCHEMBL7443029 | 0.81 | CA2 (0.35) | F2PRSS1PLGCA1CA2 | |
| SCHEMBL7441852 | 0.80 | CA2 (0.34) | F2PRSS1PLGCA1CA2 | |
| SCHEMBL7438416 | 0.77 | F2 (0.36) | F2PRSS1PLGCA1CA2 | |
| SCHEMBL7432257 | 0.76 | F2 (0.40) | F2PRSS1PLGRIPK1KMT2A | |
| SCHEMBL8098103 | 0.76 | RIPK1 (0.51) | RIPK1OPRK1KMT2AMEN1MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814622-A | COMPOUND USEFUL AS TRYPSIN LIKE SERINE PROTEASE AS THROMBIN INHIBITORS | ADIR ET COMPAGNIE (FR) | 1998-09-29 | — | — | US | disclosed |