Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 5/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8095236 | 0.87 | RIPK1 (0.52) | RIPK1POLBMMP8OPRK1SMN1; SMN2 | |
| SCHEMBL8098099 | 0.87 | RIPK1 (0.44) | RIPK1POLBMMP8OPRK1SMN1; SMN2 | |
| SCHEMBL7433686 | 0.83 | F2 (0.46) | RIPK1POLBMMP8OPRK1 | |
| SCHEMBL8095253 | 0.81 | RIPK1 (0.39) | RIPK1POLBMMP8OPRK1SMN1; SMN2 | |
| SCHEMBL10936025 | 0.79 | RIPK1 (0.63) | RIPK1MMP8OPRK1SMN1; SMN2LMNA | |
| SCHEMBL7438271 | 0.79 | F2 (0.43) | RIPK1OPRK1 | |
| SCHEMBL24486730 | 0.79 | EPHX2 (0.67) | SMN1; SMN2EPHX2LMNAGAAMEN1 | |
| SCHEMBL8095062 | 0.77 | MMP8 (0.48) | MMP8SMN1; SMN2EPHX2KEAP1NFE2L2 | |
| SCHEMBL7427096 | 0.76 | RIPK1 (0.67) | RIPK1POLBMMP8OPRK1SMN1; SMN2 | |
| Acetic Acid SCHEMBL28068598 | 0.76 | CYP2C9 (0.53) | RIPK1SMN1; SMN2GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | claimed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | claimed |
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |