Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 12/20 | 0.46 |
| ▸ | PLG | P00747 | 5/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | PLAT | P00750 | 4/20 | 0.40 |
| ▸ | F10 | P00742 | 3/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7438271 | 0.93 | F2 (0.43) | F2PLGPRSS1RIPK1PLAT | |
| SCHEMBL7438276 | 0.85 | F2 (0.38) | F2PLGPRSS1RIPK1F10 | |
| SCHEMBL8098103 | 0.83 | RIPK1 (0.51) | RIPK1OPRK1MMP8POLB | |
| SCHEMBL7432257 | 0.81 | F2 (0.40) | F2PLGPRSS1RIPK1PLAT | |
| SCHEMBL8095253 | 0.81 | RIPK1 (0.39) | RIPK1OPRK1MMP8POLB | |
| SCHEMBL26616818 | 0.80 | CTRB1 (0.59) | RIPK1OPRK1MMP8PSMB5CTRB1 | |
| SCHEMBL26616826 | 0.80 | CTRB1 (0.59) | RIPK1OPRK1MMP8PSMB5CTRB1 | |
| SCHEMBL7438592 | 0.77 | F2 (0.40) | F2PLGPRSS1PLATF10 | |
| SCHEMBL7438599 | 0.77 | F2 (0.40) | F2PLGPRSS1PLATF10 | |
| SCHEMBL8098099 | 0.76 | RIPK1 (0.44) | RIPK1OPRK1MMP8POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | claimed |
| US-5814622-A | COMPOUND USEFUL AS TRYPSIN LIKE SERINE PROTEASE AS THROMBIN INHIBITORS | ADIR ET COMPAGNIE (FR) | 1998-09-29 | — | — | US | claimed |