Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 5/20 | 0.64 |
| ▸ | CTSS | P25774 | 1/20 | 0.64 |
| ▸ | CTSK | P43235 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | CCKBR | P32239 | 4/20 | 0.58 |
| ▸ | TACR1 | P25103 | 2/20 | 0.57 |
| ▸ | ACE | P12821 | 1/20 | 0.54 |
| ▸ | CCKAR | P32238 | 2/20 | 0.52 |
| ▸ | REN | P00797 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7990614 | 0.87 | CTSL (0.71) | CTSLCTSSCTSKMAPTTP53 | |
| SCHEMBL3806534 | 0.83 | CTSL (0.72) | CTSLCTSSCTSKMAPTTP53 | |
| SCHEMBL17807348 | 0.83 | CTSL (0.80) | CTSLCTSSCTSKMAPTTP53 | |
| SCHEMBL14300166 | 0.82 | CTSL (0.76) | CTSLCTSSCTSKMAPTTP53 | |
| SCHEMBL9025972 | 0.82 | CTSL (0.76) | CTSLCTSSCTSKMAPTTP53 | |
| SCHEMBL23656831 | 0.81 | CTSL (0.74) | CTSLCTSSCTSKMAPTTP53 | |
| SCHEMBL8233750 | 0.81 | CTSL (0.74) | CTSLCTSSCTSKMAPTTP53 | |
| SCHEMBL27871524 | 0.81 | CTSL (0.76) | CTSLCTSSCTSKMAPTTP53 | |
| SCHEMBL27902245 | 0.81 | CTSL (0.76) | CTSLCTSSCTSKMAPTTP53 | |
| SCHEMBL1003555 | 0.80 | ACE (0.77) | CTSLCTSSCTSKMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703106-A | TREATING VARIOUS CARDIOVASCULAR, UROGENITAL, BRAIN DISORDERS | JAPAT LTD. (CH) | 1997-12-30 | — | — | US | disclosed |
| EP-0753004-A1 | ANTAGONISTS OF ENDOTHELIN RECEPTORS | Japat Ltd (CH) | 1997-01-15 | — | — | EP | disclosed |
| WO-1995026360-A1 | ANTAGONISTS OF ENDOTHELIN RECEPTORS | JAPAT LTD. (CH) | 1995-10-05 | — | — | WO | disclosed |