Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 5/20 | 0.71 |
| ▸ | CTSS | P25774 | 1/20 | 0.71 |
| ▸ | CTSK | P43235 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | TACR1 | P25103 | 2/20 | 0.63 |
| ▸ | ACE | P12821 | 1/20 | 0.59 |
| ▸ | CCKBR | P32239 | 4/20 | 0.56 |
| ▸ | CCKAR | P32238 | 1/20 | 0.56 |
| ▸ | REN | P00797 | 1/20 | 0.55 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.55 |
| ▸ | NMBR | P28336 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23656831 | 0.89 | CTSL (0.74) | CTSLCTSSCTSKMAPTTP53 | |
| SCHEMBL9025972 | 0.87 | CTSL (0.76) | CTSLCTSSCTSKMAPTTP53 | |
| SCHEMBL14300166 | 0.87 | CTSL (0.76) | CTSLCTSSCTSKMAPTTP53 | |
| SCHEMBL7438337 | 0.87 | CTSL (0.64) | CTSLCTSSCTSKMAPTTP53 | |
| SCHEMBL8233750 | 0.86 | CTSL (0.74) | CTSLCTSSCTSKMAPTTP53 | |
| SCHEMBL7413708 | 0.86 | CTSL (0.71) | CTSLCTSSCTSKMAPTTP53 | |
| SCHEMBL2727403 | 0.86 | CTSL (0.71) | CTSLCTSSCTSKMAPTTP53 | |
| SCHEMBL2727405 | 0.86 | CTSL (0.71) | CTSLCTSSCTSKMAPTTP53 | |
| SCHEMBL17807348 | 0.85 | CTSL (0.80) | CTSLCTSSCTSKMAPTTP53 | |
| SCHEMBL27871524 | 0.85 | CTSL (0.76) | CTSLCTSSCTSKMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991412-A4 | AMINOACYL SULFAMIDES FOR THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS | CUBIST PHARM INC (US) | 2000-06-21 | — | — | EP | disclosed |
| EP-0991412-A1 | AMINOACYL SULFAMIDES FOR THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS | Cubist Pharmaceuticals, Inc. (US) | 2000-04-12 | — | — | EP | disclosed |
| WO-1998041215-A1 | AMINOACYL SULFAMIDES FOR THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS | CUBIST PHARMACEUTICALS, INC. (US) | 1998-09-24 | — | — | WO | disclosed |