Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | EPOR | P19235 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | LAP3 | P28838 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2059549 | 1.00 | CTRB1 (0.49) | CTRB1ALDH1A1TDP1MAPK1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL28475258 | 0.98 | CTRB1 (0.48) | CTRB1ALDH1A1TDP1MAPK1L3MBTL1 | |
| SCHEMBL13535120 | 0.94 | LMNA (0.49) | CTRB1ALDH1A1TDP1MAPK1L3MBTL1 | |
| SCHEMBL2440503 | 0.92 | EPOR (0.43) | CTRB1ALDH1A1KMT2AEPORLTA4H | |
| SCHEMBL21295477 | 0.92 | EPOR (0.43) | CTRB1ALDH1A1TDP1MAPK1L3MBTL1 | |
| SCHEMBL21295478 | 0.92 | EPOR (0.43) | CTRB1ALDH1A1TDP1MAPK1L3MBTL1 | |
| SCHEMBL13535122 | 0.92 | EPOR (0.46) | CTRB1ALDH1A1L3MBTL1EPORLTA4H | |
| Hydrochloric Acid SCHEMBL21295474 | 0.90 | EPOR (0.42) | CTRB1ALDH1A1TDP1MAPK1L3MBTL1 | |
| SCHEMBL2438787 | 0.90 | LTA4H (0.60) | L3MBTL1EPORLTA4HLAP3 | |
| SCHEMBL21295480 | 0.89 | EPOR (0.42) | CTRB1ALDH1A1TDP1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105152978-B | A kind of preparation method of the butanol of 3 tert-butoxycarbonylamino of (2R, 3S) 1 chlorine, 4 phenyl 2 | 上海应用技术学院 | 2017-08-25 | — | — | CN | claimed |
| CN-105152978-A | Preparation method for (2R,3S)-1-chlorine-3-tert-butoxycarbonylamino-4-phenyl-2-butanol | SHANGHAI INST TECHNOLOGY | 2015-12-16 | — | — | CN | claimed |
| CN-105152978-B | A kind of preparation method of the butanol of 3 tert-butoxycarbonylamino of (2R, 3S) 1 chlorine, 4 phenyl 2 | 上海应用技术学院 | 2017-08-25 | — | — | CN | disclosed |
| CN-106380412-A | Method for synthesizing ritonavir intermediate | 中国科学院新疆生态与地理研究所 | 2017-02-08 | — | — | CN | disclosed |
| CN-105152978-A | Preparation method for (2R,3S)-1-chlorine-3-tert-butoxycarbonylamino-4-phenyl-2-butanol | SHANGHAI INST TECHNOLOGY | 2015-12-16 | — | — | CN | disclosed |
| CN-102060732-A | 5-amino-4-hydroxy-N-aryl azelamide derivatives as well as preparation methods and medical applications thereof | JIANGSU HENGRUI MEDICINE CO | 2011-05-18 | — | — | CN | disclosed |
| US-7649015-B2 | Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds | GILEAD SCIENCES, INC. (US) | 2010-01-19 | — | — | US | disclosed |
| US-7649015-B2 | Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds | GILEAD SCIENCES, INC. (US) | 2010-01-19 | — | — | US | disclosed |
| US-20070010489-A1 | Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds | GILEAD SCIENCES, INC. | 2007-01-11 | — | — | US | disclosed |
| US-6281379-B1 | HALOGENATING G-AMINO-B-KETO SULFOXIDE; REACTING WITH ACID AND ALCOHOL; FORMING B-AMINO-A-HYDROXY ACID COMPOUNDS | KANEKA CORPORATION (JP) | 2001-08-28 | — | — | US | disclosed |
| EP-1055664-A1 | Process for producing norstatin derivatives | KANEKA CORPORATION (JP) | 2000-11-29 | — | — | EP | disclosed |
| US-5932766-A | Process for the preparation of substituted keto-enamines | ABBOTT LABORATORIES (US) | 1999-08-03 | — | — | US | disclosed |
| WO-1998054122-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED KETO-ENAMINES | ABBOTT LABORATORIES (US) | 1998-12-03 | — | — | WO | disclosed |
| EP-0769936-A1 | SELF-EMULSIFYING DRUG DELIVERY SYSTEM | G.D. SEARLE & CO. (US) | 1997-05-02 | — | — | EP | disclosed |
| EP-0724563-A1 | PROCESS FOR THE PREPARATION OF A SUBSTITUTED 2,5-DIAMINO-3-HYDROXYHEXANE | ABBOTT LABORATORIES (US) | 1996-08-07 | — | — | EP | disclosed |
| WO-1996003113-A1 | SELF-EMULSIFYING DRUG DELIVERY SYSTEM | G.D. SEARLE & CO. (US) | 1996-02-08 | — | — | WO | disclosed |
| EP-0674513-A4 | — | — | 1995-10-25 | — | — | EP | disclosed |
| EP-0674513-A1 | RETROVIRAL PROTEASE INHIBITING COMPOUNDS. | ABBOTT LAB (US) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994014436-A1 | RETROVIRAL PROTEASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1994-07-07 | — | — | WO | disclosed |
| US-4990669-A | Optically active α-amino aldehydes, process for the preparation thereof, and the use thereof for the stereoselective preparation of optically active β-amino alcohols | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010489-A1 | Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds | PPA1, PNP, PPME1 | CTRB1 1119/4885ALDH1A1 3337/4885TDP1 607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.