Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 18/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892093 | 0.93 | REN (0.42) | REN | |
| SCHEMBL7431575 | 0.93 | REN (0.42) | REN | |
| SCHEMBL7431468 | 0.93 | CTSS (0.40) | RENCTSLCTSBCTSS | |
| SCHEMBL8891461 | 0.92 | PSMB1 (0.44) | REN | |
| SCHEMBL8892662 | 0.92 | REN (0.42) | REN | |
| SCHEMBL7429993 | 0.88 | REN (0.43) | REN | |
| SCHEMBL8893998 | 0.88 | CTSS (0.39) | RENCTSLCTSBCTSS | |
| SCHEMBL7435576 | 0.88 | CTSD (0.40) | RENCTSLCTSBCTSS | |
| SCHEMBL7434937 | 0.87 | REN (0.41) | REN | |
| SCHEMBL7435623 | 0.85 | PSEN1 (0.40) | RENCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643878-A | TREATMENT OF RETROVIRAL DISEASES LIKE AIDS | CIBA-GEIGY CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| EP-0532466-A2 | Derivatives of 5-amino-4-hydroxy-hexanoic acid and their therapeutical use | CIBA-GEIGY AG (CH) | 1993-03-17 | — | — | EP | disclosed |