Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 8/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | CTSE | P14091 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9677769 | 1.00 | REN (0.43) | RENCTSSCTSKCTSDCTSE | |
| SCHEMBL9551921 | 1.00 | REN (0.43) | RENCTSSCTSKCTSDCTSE | |
| SCHEMBL9676600 | 1.00 | REN (0.43) | RENCTSSCTSKCTSDCTSE | |
| SCHEMBL9676607 | 1.00 | REN (0.43) | RENCTSSCTSKCTSDCTSE | |
| SCHEMBL10866353 | 1.00 | REN (0.43) | RENCTSSCTSKCTSDCTSE | |
| SCHEMBL9676521 | 0.86 | CA1 (0.46) | CTSSCTSKCA1CA2CA7 | |
| SCHEMBL9675593 | 0.86 | CA1 (0.46) | CTSSCTSKCA1CA2CA7 | |
| SCHEMBL7445228 | 0.84 | CA1 (0.44) | CTSSCTSKCA1CA2CA7 | |
| SCHEMBL7438624 | 0.83 | CA1 (0.40) | RENCTSSCTSKCTSDCTSE | |
| SCHEMBL9677665 | 0.83 | REN (0.54) | RENCTSSCTSKCTSDCTSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5222063-A | — | — | None | — | — | JP | disclosed |
| JP-H05222063-A | INTERMEDIATE FOR RENIN INHIBITORY POLYPEPTIDE | UPJOHN CO:THE | 1993-08-31 | — | — | JP | disclosed |
| EP-0486478-A2 | Renin-inhibiting peptides | THE UPJOHN COMPANY (US) | 1992-05-20 | — | — | EP | disclosed |
| US-4880781-A | HYPOTENSIVE AGENTS | THE UPJOHN COMPANY (US) | 1989-11-14 | — | — | US | disclosed |
| EP-0173481-A2 | Peptides | THE UPJOHN COMPANY (US) | 1986-03-05 | — | — | EP | disclosed |