Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9638271 | 0.82 | DGAT1 (0.41) | DGAT1 | |
| SCHEMBL7843607 | 0.76 | ESR1 (0.47) | DGAT1 | |
| SCHEMBL7683886 | 0.76 | PDE10A (0.30) | — | |
| SCHEMBL1441203 | 0.75 | DGAT1 (0.46) | DGAT1 | |
| SCHEMBL2153326 | 0.75 | DGAT1 (0.40) | DGAT1 | |
| SCHEMBL1488779 | 0.74 | KMT2A (0.43) | DGAT1 | |
| SCHEMBL3574886 | 0.73 | DGAT1 (0.42) | DGAT1 | |
| SCHEMBL18865495 | 0.73 | DGAT1 (0.39) | DGAT1 | |
| SCHEMBL28937619 | 0.73 | DGAT1 (0.39) | DGAT1 | |
| SCHEMBL7507611 | 0.72 | PDE10A (0.45) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710153-A | INTERLEUKIN CONVERTING ENZYME INHIBITORS | ONO PHRAMACEUTICAL CO., LTD. (JP) | 1998-01-20 | — | — | US | disclosed |
| EP-0761680-A2 | Tetrazole compounds having Interleukin-1beta converting enzyme inhibitory activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-03-12 | — | — | EP | disclosed |