Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7439208 | 0.76 | DGAT1 (0.36) | — | |
| SCHEMBL1767760 | 0.74 | DGAT1 (0.35) | PDE10A | |
| SCHEMBL3939670 | 0.73 | TBXAS1 (0.34) | PDE10A | |
| SCHEMBL4025619 | 0.72 | — | — | |
| SCHEMBL9638271 | 0.72 | DGAT1 (0.41) | PDE10A | |
| SCHEMBL16203617 | 0.71 | ACHE (0.35) | — | |
| SCHEMBL3574886 | 0.70 | DGAT1 (0.42) | — | |
| SCHEMBL1488779 | 0.68 | KMT2A (0.43) | — | |
| SCHEMBL7605831 | 0.68 | DGAT1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL15455783 | 0.67 | DGAT1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376484-B1 | FOR PREVENTION AND/OR TREATMENT OF VARIOUS KINDS OF INFLAMMATORY DISEASE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-04-23 | — | — | US | disclosed |
| US-6136834-A | TETRAZOLE PEPTIDES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0900791-A1 | TETRAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-10 | — | — | EP | disclosed |