Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.38 |
| ▸ | SCD | O00767 | 2/20 | 0.38 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | CPT1A | P50416 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27570769 | 0.95 | APP (0.43) | APPNPC1RAB9ASCDSCD5 | |
| SCHEMBL7432425 | 0.89 | MEN1 (0.47) | APPNPC1RAB9A | |
| SCHEMBL7429230 | 0.88 | RAB9A (0.45) | SMN1; SMN2APPNPC1RAB9AHPGD | |
| SCHEMBL7583778 | 0.88 | FFAR1 (0.44) | SMN1; SMN2APPNPC1RAB9AFFAR1 | |
| SCHEMBL27570759 | 0.84 | GRM5 (0.43) | APPNPC1RAB9AFFAR1ALDH1A1 | |
| SCHEMBL27570763 | 0.84 | FFAR1 (0.44) | APPNPC1RAB9AFFAR1 | |
| SCHEMBL27578899 | 0.83 | NPC1 (0.44) | NPC1RAB9ASCDSCD5FFAR1 | |
| SCHEMBL7422672 | 0.83 | FFAR1 (0.48) | NPC1RAB9AFFAR1ALDH1A1 | |
| SCHEMBL7433078 | 0.83 | FFAR1 (0.42) | NPC1RAB9AFFAR1CPT1A | |
| SCHEMBL7487553 | 0.83 | FFAR1 (0.42) | NPC1RAB9AFFAR1CPT1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244656-A1 | NON-PEPTIDYL INHIBITORS OF VLA-4 DEPENDENT CELL BINDING USEFUL IN TREATING INFLAMMATORY, AUTOIMMUNE, AND RESPIRATORY DISEASES | Pfizer Products Inc. (US) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001051487-A1 | NON-PEPTIDYL INHIBITORS OF VLA-4 DEPENDENT CELL BINDING USEFUL IN TREATING INFLAMMATORY, AUTOIMMUNE, AND RESPIRATORY DISEASES | PFIZER PRODUCTS INC. (US) | 2001-07-19 | — | — | WO | disclosed |