SCHEMBL7439894

SCHEMBL7439894

CC(=O)SCC(CCc1cccc(C)c1)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.44
CPB2 Q96IY4 1/20 0.43
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
MAPT P10636 1/20 0.41
ANPEP P15144 2/20 0.40
ERAP2 Q6P179 1/20 0.40
ERAP1 Q9NZ08 1/20 0.40
MME P08473 1/20 0.40
CTBP2 P56545 1/20 0.40
MMP1 P03956 1/20 0.39
MMP13 P45452 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
ABCC3 O15438 1/20 0.39
NR1I2 O75469 1/20 0.39
ABCB11 O95342 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6294971 0.86 CPB2 (0.50) CPB2ANPEPERAP2ERAP1MME
SCHEMBL9469381 0.81 TAAR1 (0.46) TAAR1MEN1KMT2AMAPTANPEP
SCHEMBL7429430 0.77 GRIK1 (0.56) CPB2MMEMMP1CYP1A2CYP3A4
SCHEMBL8167065 0.76 CPB2 (0.57) CPB2MAPTMMEMMP1CYP1A2
SCHEMBL15093693 0.75 MEN1 (0.50) TAAR1MEN1KMT2AMAPTCTBP2
SCHEMBL30963031 0.75 MEN1 (0.50) TAAR1MEN1KMT2AMAPTCTBP2
SCHEMBL17929000 0.75 MEN1 (0.50) TAAR1MEN1KMT2AMAPTCTBP2
SCHEMBL8168663 0.75 CPB2 (0.60) CPB2MAPTMMEMMP1CYP1A2
SCHEMBL7396931 0.74 LDHA (0.49) TAAR1CPB2ALDH1A1
SCHEMBL5342823 0.74 KIF11 (0.56) TAAR1MEN1KMT2AMAPTANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4929641-A DIURETICS, ANGIOTENSIN CONVERTING ENZYMES SCHERING CORPORATION (US) 1990-05-29 US disclosed