Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | RARG | P13631 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7435674 | 0.79 | CHRM1 (0.36) | MMECYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL7435783 | 0.79 | CPA3 (0.36) | CYP2C9CYP2C19KDM4EMAPTHSD17B10 | |
| SCHEMBL7440319 | 0.75 | CNR1 (0.38) | CYP2C9CYP2C19CYP1A2CYP3A4CNR1 | |
| SCHEMBL7435787 | 0.67 | DAO (0.36) | MAPTMEN1POLBKMT2ATSHR | |
| SCHEMBL27337151 | 0.66 | MME (0.49) | MMECYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL6154521 | 0.65 | CYP1A2 (0.63) | MMECYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL1337302 | 0.65 | ALPI (0.55) | MMECYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL838961 | 0.65 | CYP1A2 (0.63) | MMECYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL838962 | 0.65 | CYP1A2 (0.63) | MMECYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL859558 | 0.65 | ALPI (0.55) | MMECYP2C9CYP2C19CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |