Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7435682 | 0.79 | KMT2A (0.37) | CNR1CNR2ALDH1A1POLBMEN1 | |
| SCHEMBL7435787 | 0.76 | DAO (0.36) | CNR2TSHRGAAABCB1POLB | |
| SCHEMBL7188715 | 0.67 | KMT2A (0.56) | CNR2TSHRHPGDALDH1A1POLB | |
| SCHEMBL7307985 | 0.66 | ACE (0.47) | CNR2TSHRHPGDALDH1A1MEN1 | |
| SCHEMBL7307992 | 0.66 | ACE (0.47) | CNR2TSHRHPGDALDH1A1MEN1 | |
| SCHEMBL13970215 | 0.66 | ALDH1A1 (0.43) | CNR1CNR2TSHRHPGDALDH1A1 | |
| SCHEMBL7037470 | 0.64 | MMP12 (0.47) | TSHRHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL24327924 | 0.63 | PGR (0.49) | HPGDALDH1A1KMT2AHTTGLA | |
| SCHEMBL264757 | 0.63 | GSK3A (0.54) | TSHRGAAMEN1KMT2AHTT | |
| SCHEMBL8171507 | 0.63 | TSHR (0.46) | TSHRHPGDGAAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |