Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | MME | P08473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7439905 | 0.86 | MDM2 (0.36) | CHRM1HSD17B10ALDH1A1MDM2CYP2C9 | |
| SCHEMBL7440962 | 0.81 | HSD11B1 (0.37) | CHRM1MMEALDH1A1MDM2ACE | |
| SCHEMBL7440310 | 0.79 | MME (0.38) | MMEHSD17B10ALDH1A1ACECYP2C9 | |
| SCHEMBL7435682 | 0.78 | KMT2A (0.37) | ALDH1A1ACECNR1MEN1POLB | |
| SCHEMBL7439919 | 0.76 | KMT2A (0.39) | ALDH1A1ACETSHRMEN1POLB | |
| SCHEMBL10806394 | 0.63 | TDP1 (0.55) | MMEALDH1A1CYP2C9CYP2C19TSHR | |
| SCHEMBL7436246 | 0.62 | MME (0.40) | MMEACE | |
| SCHEMBL5669039 | 0.62 | FPR2 (0.54) | ALDH1A1CYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL10880476 | 0.62 | MME (0.46) | MMEALDH1A1ACECYP2C9CYP2C19 | |
| SCHEMBL838961 | 0.62 | CYP1A2 (0.63) | MMECYP2C9CYP2C19CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |