Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ACE | P12821 | 11/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7439919 | 0.84 | KMT2A (0.39) | KMT2AACEALDH1A1MEN1POLB | |
| SCHEMBL7440967 | 0.78 | KMT2A (0.37) | KMT2AACEALDH1A1MEN1POLB | |
| SCHEMBL7435674 | 0.78 | CHRM1 (0.36) | KMT2AACEALDH1A1MEN1CNR1 | |
| SCHEMBL7439905 | 0.76 | MDM2 (0.36) | KMT2AALDH1A1MEN1POLBNPSR1 | |
| SCHEMBL7440962 | 0.71 | HSD11B1 (0.37) | KMT2AACEALDH1A1MEN1 | |
| SCHEMBL7188715 | 0.63 | KMT2A (0.56) | KMT2AALDH1A1MEN1CNR2POLB | |
| SCHEMBL7436249 | 0.63 | ACE (0.42) | KMT2AACEALDH1A1MEN1 | |
| SCHEMBL7307985 | 0.62 | ACE (0.47) | KMT2AACEALDH1A1MEN1CNR2 | |
| SCHEMBL7307992 | 0.62 | ACE (0.47) | KMT2AACEALDH1A1MEN1CNR2 | |
| SCHEMBL13970215 | 0.62 | ALDH1A1 (0.43) | KMT2AALDH1A1MEN1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |