Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LTA4H | P09960 | 4/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7447128 | 0.89 | RAB9A (0.52) | MEN1KMT2APOLBRAB9ALMNA | |
| SCHEMBL7430532 | 0.89 | KMT2A (0.39) | MEN1KMT2APOLBRAB9ALMNA | |
| SCHEMBL7435658 | 0.89 | CNR2 (0.44) | MEN1KMT2APOLBRAB9ALMNA | |
| SCHEMBL7439756 | 0.89 | POLB (0.45) | POLBRAB9ALMNAALDH1A1LTA4H | |
| SCHEMBL7445143 | 0.88 | POLB (0.42) | MEN1KMT2APOLBRAB9ALMNA | |
| SCHEMBL7443888 | 0.88 | POLB (0.48) | POLBRAB9ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7445153 | 0.88 | MAPT (0.36) | MEN1KMT2APOLBLMNAALDH1A1 | |
| SCHEMBL10997102 | 0.88 | MEN1 (0.52) | MEN1KMT2APOLBRAB9ALMNA | |
| SCHEMBL7439415 | 0.87 | POLB (0.49) | POLBRAB9ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7438128 | 0.87 | POLB (0.42) | MEN1KMT2APOLBRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | claimed |
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |