Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7444281 | 0.89 | NAMPT (0.46) | LMNASMN1; SMN2ADRB3MAPTKMT2A | |
| SCHEMBL7440389 | 0.89 | MEN1 (0.47) | LTA4HLMNARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7432904 | 0.88 | LTA4H (0.44) | LTA4HLMNASMN1; SMN2HPGDMAPT | |
| SCHEMBL7428109 | 0.88 | LMNA (0.52) | LMNARAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL7431708 | 0.88 | FAAH (0.45) | LMNASMN1; SMN2MAPTDRD2 | |
| SCHEMBL7434127 | 0.86 | ALOX5 (0.47) | LMNARAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL7438986 | 0.85 | SMN1; SMN2 (0.50) | LMNARAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL7446120 | 0.82 | MAPT (0.44) | LTA4HLMNASMN1; SMN2HPGDMAPT | |
| SCHEMBL7440385 | 0.82 | LTA4H (0.38) | LTA4HLMNANPC1SMN1; SMN2HPGD | |
| SCHEMBL7440356 | 0.81 | POLB (0.43) | LTA4HLMNARAB9ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |