Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 6/20 | 0.36 |
| ▸ | MMP3 | P08254 | 3/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | MDM4 | O15151 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442501 | 0.91 | MEN1 (0.41) | CTSKMAPTKMT2AMEN1 | |
| SCHEMBL7442611 | 0.89 | ALDH1A1 (0.37) | TSHRMMP2MMP3LMNAMAPT | |
| SCHEMBL7429949 | 0.89 | ALDH1A1 (0.37) | TSHRMMP2MMP3LMNAMAPT | |
| SCHEMBL7441757 | 0.89 | POLB (0.37) | CTSSCTSKKMT2AMEN1 | |
| SCHEMBL7441749 | 0.89 | POLB (0.37) | CTSSCTSKKMT2AMEN1 | |
| SCHEMBL7429954 | 0.89 | ALDH1A1 (0.37) | TSHRMMP2MMP3LMNAMAPT | |
| SCHEMBL7443773 | 0.87 | METAP2 (0.36) | — | |
| SCHEMBL7431633 | 0.87 | METAP2 (0.36) | — | |
| SCHEMBL7431641 | 0.87 | METAP2 (0.36) | — | |
| SCHEMBL7429900 | 0.83 | KMT2A (0.39) | TSHRLMNAMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187905-B1 | PEPTIDE COMPOUND WHICH INHIBITS VIRAL PROTEINASES; VIRICIDES FOR HEPATITIS C, HEPATITIS G, AND HUMAN GB VIRUSES | HOFFMANN-LA ROCHE INC. | 2001-02-13 | — | — | US | disclosed |