Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7445420 | 0.89 | EPHX2 (0.38) | EPHX2 | |
| SCHEMBL7434161 | 0.89 | TPSAB1 (0.32) | EPHX2 | |
| SCHEMBL7441218 | 0.87 | ALDH1A1 (0.45) | KMT2AMEN1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL7431992 | 0.86 | L3MBTL1 (0.44) | KMT2AMEN1ALDH1A1CA2MAPT | |
| SCHEMBL7438937 | 0.85 | OPRM1 (0.43) | KMT2AMEN1ALDH1A1CYP2D6MAPT | |
| SCHEMBL7440649 | 0.83 | TSHR (0.36) | KMT2AMEN1TSHRSMN1; SMN2MAPT | |
| SCHEMBL7442501 | 0.82 | MEN1 (0.41) | KMT2AMEN1MAPTMMP8 | |
| SCHEMBL7441757 | 0.81 | POLB (0.37) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL7442611 | 0.81 | ALDH1A1 (0.37) | HPGDTSHRALDH1A1RIPK1MAPT | |
| SCHEMBL7429954 | 0.81 | ALDH1A1 (0.37) | HPGDTSHRALDH1A1RIPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187905-B1 | PEPTIDE COMPOUND WHICH INHIBITS VIRAL PROTEINASES; VIRICIDES FOR HEPATITIS C, HEPATITIS G, AND HUMAN GB VIRUSES | HOFFMANN-LA ROCHE INC. | 2001-02-13 | — | — | US | disclosed |