Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7433751 | 0.88 | SLC1A2 (0.57) | RAB9ASMN1; SMN2SLC1A2PPARGPPARA | |
| SCHEMBL7488786 | 0.84 | SLC1A2 (0.50) | NPC1RAB9ASMN1; SMN2SLC1A2PPARG | |
| SCHEMBL7496499 | 0.83 | PPARG (0.48) | NPC1RAB9ASMN1; SMN2SLC1A2PPARG | |
| SCHEMBL16235034 | 0.78 | CCR1 (0.60) | ALDH1A1LMNAKMT2ACCR1HTT | |
| SCHEMBL16234990 | 0.78 | CCR1 (0.60) | ALDH1A1LMNAKMT2ACCR1HTT | |
| SCHEMBL7434063 | 0.77 | CES2 (0.43) | SMN1; SMN2SLC1A2ALDH1A1LMNAKMT2A | |
| SCHEMBL16283734 | 0.77 | CA2 (0.63) | SLC1A2PPARGPPARACA2CA1 | |
| SCHEMBL7497460 | 0.76 | SLC1A2 (0.48) | SMN1; SMN2SLC1A2PPARGPPARAALDH1A1 | |
| SCHEMBL14119283 | 0.76 | RAB9A (0.54) | NPC1RAB9ASMN1; SMN2CA2CA1 | |
| SCHEMBL7432066 | 0.76 | RAB9A (0.54) | NPC1RAB9ASMN1; SMN2UTS2RKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4453003-A | ENZYME INHIBITORS, ANTIINFLAMMATORY AGENTS | UMEZAWA HAMAO (JP) | 1984-06-05 | — | — | US | disclosed |
| US-4391986-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediates therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1983-07-05 | — | — | US | disclosed |
| US-4281180-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediated therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1981-07-28 | — | — | US | disclosed |