Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7433751 | 0.92 | SLC1A2 (0.57) | SLC1A2KMT2AMAPTTSHRSMN1; SMN2 | |
| SCHEMBL7497460 | 0.85 | SLC1A2 (0.48) | SLC1A2KMT2AMAPTTSHRSMN1; SMN2 | |
| SCHEMBL7440689 | 0.84 | NPC1 (0.47) | SLC1A2KMT2AMAPTTSHRSMN1; SMN2 | |
| SCHEMBL7496442 | 0.81 | LMNA (0.40) | KMT2AMAPTTSHRALDH1A1HTT | |
| SCHEMBL7496499 | 0.81 | PPARG (0.48) | SLC1A2KMT2ASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL7434063 | 0.78 | CES2 (0.43) | SLC1A2KMT2AMAPTTSHRSMN1; SMN2 | |
| SCHEMBL7441717 | 0.75 | TSHR (0.43) | SLC1A2KMT2AMAPTTSHRSMN1; SMN2 | |
| SCHEMBL7434399 | 0.74 | ESR1 (0.46) | TSHRSMN1; SMN2ALDH1A1HTTCA1 | |
| SCHEMBL5908060 | 0.74 | SLC1A2 (0.75) | SLC1A2KMT2ASMN1; SMN2ALDH1A1CA1 | |
| SCHEMBL7436665 | 0.74 | ALDH1A1 (0.44) | SLC1A2KMT2AMAPTTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4453003-A | ENZYME INHIBITORS, ANTIINFLAMMATORY AGENTS | UMEZAWA HAMAO (JP) | 1984-06-05 | — | — | US | disclosed |
| US-4391986-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediates therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1983-07-05 | — | — | US | disclosed |
| US-4281180-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediated therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1981-07-28 | — | — | US | disclosed |