Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 11/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | CHKA | P35790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7428297 | 0.87 | HTR1A (0.53) | HTR1ASLC7A5SLC6A4HRH3SLC6A9 | |
| SCHEMBL7443700 | 0.87 | HTR1A (0.63) | HTR1ASLC6A4 | |
| SCHEMBL7431833 | 0.78 | HTR1A (0.74) | HTR1ASLC6A4HRH3KDM4ESLC6A9 | |
| SCHEMBL7442963 | 0.77 | HTR1A (0.51) | HTR1ASLC7A5SLC6A4HRH3KDM4E | |
| SCHEMBL7427779 | 0.74 | SLC7A5 (0.61) | HTR1ASLC7A5SLC6A4HRH3 | |
| SCHEMBL7427735 | 0.72 | HTR1A (0.67) | HTR1ASLC7A5 | |
| SCHEMBL7434915 | 0.72 | HTR1A (0.71) | HTR1ASLC6A4HRH3KDM4E | |
| SCHEMBL7434240 | 0.70 | SLC6A4 (0.61) | HTR1ASLC6A4HRH3 | |
| SCHEMBL29240977 | 0.70 | HTR1A (0.39) | HTR1AKDM4ETDP1 | |
| SCHEMBL29240972 | 0.70 | HTR1A (0.39) | HTR1AKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571685-A1 | Aryloxyheteroarylpropylamines, their preparation and use | NOVO NORDISK A/S (DK) | 1993-12-01 | — | — | EP | disclosed |