Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.40 |
| ▸ | CPA3 | P15088 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426767 | 0.86 | ACE (0.37) | ACECPA3FOLH1ALDH1A1GAA | |
| SCHEMBL7441046 | 0.84 | CPA3 (0.38) | ACECPA3FOLH1ALDH1A1GAA | |
| SCHEMBL7435582 | 0.82 | ACE (0.40) | ACECPA3FOLH1ALDH1A1GAA | |
| SCHEMBL7432557 | 0.82 | ACE (0.40) | ACECPA3FOLH1ALDH1A1GAA | |
| SCHEMBL7437087 | 0.81 | ACE (0.37) | ACECPA3FOLH1ALDH1A1GAA | |
| SCHEMBL7440995 | 0.78 | ATM (0.43) | ACEATMALDH1A1POLB | |
| SCHEMBL7434177 | 0.74 | HSD11B1 (0.38) | ACEALDH1A1GAATDP1 | |
| SCHEMBL7428787 | 0.72 | KMT2A (0.45) | ACECPA3FOLH1ALDH1A1MME | |
| SCHEMBL7436233 | 0.71 | MME (0.39) | ACEMME | |
| SCHEMBL7432267 | 0.71 | AMPD2 (0.36) | ALDH1A1GAATDP1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |