Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426769 | 0.86 | ATM (0.39) | ATMACEPOLBNPSR1CNR2 | |
| SCHEMBL7441051 | 0.84 | ATM (0.37) | ATMACEPOLBNPSR1CNR2 | |
| SCHEMBL7440989 | 0.78 | ACE (0.40) | ATMACEPOLBALDH1A1 | |
| SCHEMBL7434183 | 0.74 | ALDH1A1 (0.37) | POLBTSHRKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7428792 | 0.72 | CYP2D6 (0.45) | ACEPOLBNPSR1CYP2D6CYP2C9 | |
| SCHEMBL7436241 | 0.71 | ACE (0.42) | ACEPOLB | |
| SCHEMBL7432273 | 0.71 | AMPD2 (0.37) | POLBNPSR1KMT2AALDH1A1 | |
| SCHEMBL7434091 | 0.71 | ACE (0.41) | ACEPOLB | |
| SCHEMBL7443207 | 0.70 | ACE (0.41) | ACE | |
| SCHEMBL7439237 | 0.70 | ACE (0.41) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |