Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MMP8 | P22894 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
| ▸ | PPID | Q08752 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28796267 | 0.93 | ALDH1A1 (0.49) | ALDH1A1MMP8RECQLPIN1PPID | |
| SCHEMBL28796243 | 0.92 | ALDH1A1 (0.48) | ALDH1A1MMP8RECQLPIN1KMT2A | |
| SCHEMBL28796264 | 0.92 | ALDH1A1 (0.48) | ALDH1A1MMP8RECQLPIN1LMNA | |
| SCHEMBL28796282 | 0.92 | MMP8 (0.51) | ALDH1A1MMP8RECQLPIN1PPID | |
| SCHEMBL28796256 | 0.91 | ALDH1A1 (0.47) | ALDH1A1MMP8RECQLPOLBLMNA | |
| SCHEMBL28796335 | 0.87 | AR (0.44) | ALDH1A1MMP8RECQLSMN1; SMN2LMNA | |
| SCHEMBL29048912 | 0.87 | MMP8 (0.46) | ALDH1A1MMP8RECQLPIN1PPID | |
| SCHEMBL9555278 | 0.84 | PTPN1 (0.47) | ALDH1A1MMP8RECQLSMN1; SMN2LMNA | |
| SCHEMBL23699289 | 0.83 | MMP8 (0.57) | ALDH1A1MMP8RECQLPIN1PPID | |
| SCHEMBL29277135 | 0.83 | ALDH1A1 (0.54) | ALDH1A1MMP8RECQLPIN1PPID |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109694334-B | Solvent-free preparation method of disubstituted cyanoacetate compound | 西华大学 | 2022-07-22 | — | — | CN | disclosed |
| CN-109694334-A | The non-solvent preparation of disubstituted cyanoacetic acid ester compounds | 西华大学 | 2019-04-30 | — | — | CN | disclosed |
| US-6239236-B1 | COMPRISING TI, MG, HALOGEN AND AN ELECTRON DONOR COMPOUND SELECTED FROM CYANOESTERS | MONTELL TECHNOLOGY COMPANY B.V. (NL) | 2001-05-29 | — | — | US | disclosed |
| US-6143684-A | FOR STEREOSPECIFIC POLYMERIZATION OF OLEFINS SUCH AS PROPYLENE | MONTELL TECHNOLOGY COMPANY B.V. (NL) | 2000-11-07 | — | — | US | disclosed |
| US-5250517-A | Hypotensive and cardiotonic agents; cardiac insufficiency | HOFFMANN-LA ROCHE INC. (US) | 1993-10-05 | — | — | US | disclosed |
| US-5190922-A | Antiinflammatory | ABBOTT LABORATORIES (US) | 1993-03-02 | — | — | US | disclosed |
| WO-1992021361-A1 | TERMINALLY MODIFIED TRI-, TETRA- AND PENTAPEPTIDE ANAPHYLATOXIN RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 1992-12-10 | — | — | WO | disclosed |