Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 7/20 | 0.53 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.50 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.42 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.42 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28145263 | 1.00 | GRIK1 (0.53) | GRIK1GRIK2DPP7GRIA1GRIA2 | |
| SCHEMBL25660395 | 0.90 | GRIK1 (0.46) | GRIK1GRIK2GRIA1GRIA2GRIA4 | |
| SCHEMBL10794617 | 0.81 | CES2 (0.44) | GRIK1GRIK2CES2CES1ALDH1A1 | |
| SCHEMBL8531959 | 0.81 | CES2 (0.44) | GRIK1GRIK2CES2CES1ALDH1A1 | |
| SCHEMBL5322747 | 0.77 | GRIK1 (0.46) | GRIK1GRIK2DPP7GRIA1GRIA2 | |
| Biphenyl SCHEMBL7779237 | 0.76 | GRIK1 (0.53) | GRIK1GRIK2DPP7GRIA1GRIA2 | |
| SCHEMBL25660565 | 0.74 | GRIK1 (0.38) | GRIK1GRIK2GRIA1GRIA2GRIA4 | |
| SCHEMBL10102754 | 0.73 | SLC1A3 (0.37) | GRIK1CES2CES1ALDH1A1SLC1A3 | |
| SCHEMBL5909830 | 0.72 | CES2 (0.44) | CES2CES1ALDH1A1 | |
| SCHEMBL29634987 | 0.72 | ALDH1A1 (0.47) | GRIK1GRIK2GRM2CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |