Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 16/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6962120 | 0.81 | GRIN1 (1.00) | GRIN1 | |
| SCHEMBL7449620 | 0.81 | GRIN1 (0.69) | GRIN1 | |
| SCHEMBL7246879 | 0.78 | DRD2 (0.54) | GRIN1 | |
| SCHEMBL8547729 | 0.75 | ALDH1A1 (0.47) | GRIN1 | |
| SCHEMBL12619204 | 0.74 | GRIN1 (1.00) | GRIN1 | |
| SCHEMBL8548421 | 0.74 | LMNA (0.43) | GRIN1 | |
| SCHEMBL13349468 | 0.71 | ALDH1A1 (0.42) | — | |
| SCHEMBL5888859 | 0.70 | DRD2 (0.41) | — | |
| SCHEMBL5888846 | 0.68 | — | — | |
| SCHEMBL5888885 | 0.68 | DRD2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869791-A4 | 4-SUBSTITUTED PIPERIDINE ANALOGS AND THEIR USE AS SUBTYPE SELECTIVE NMDA RECEPTOR ANTAGONISTS | WARNER LAMBERT CO (US) | 1999-04-28 | — | — | EP | claimed |
| EP-0869791-A1 | 4-SUBSTITUTED PIPERIDINE ANALOGS AND THEIR USE AS SUBTYPE SELECTIVE NMDA RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1998-10-14 | — | — | EP | claimed |
| WO-1997023214-A1 | 4-SUBSTITUTED PIPERIDINE ANALOGS AND THEIR USE AS SUBTYPE SELECTIVE NMDA RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1997-07-03 | — | — | WO | claimed |