Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 4/20 | 0.52 |
| ▸ | RNASEH1 | O60930 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
| ▸ | PNP | P00491 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL359546 | 0.87 | PDE2A (0.51) | PDE2ARNASEH1ALDH1A1CCNE2CCNE1 | |
| SCHEMBL7440929 | 0.86 | PDE2A (0.54) | PDE2ARNASEH1CCNE2CCNE1CDK2 | |
| SCHEMBL6024717 | 0.83 | PDE2A (0.46) | PDE2ARNASEH1KMT2AKDM4EALDH1A1 | |
| SCHEMBL6023491 | 0.83 | PDE2A (0.44) | PDE2ARNASEH1PNP | |
| SCHEMBL6024368 | 0.83 | PDE2A (0.46) | PDE2ARNASEH1ALDH1A1CCNE2CCNE1 | |
| SCHEMBL6023455 | 0.83 | PDE2A (0.43) | PDE2ARNASEH1CCNE2CCNE1CDK2 | |
| SCHEMBL6051959 | 0.82 | PDE2A (0.63) | PDE2ARNASEH1KMT2AKDM4EADORA3 | |
| SCHEMBL7436563 | 0.81 | PDE2A (0.57) | PDE2ARNASEH1KMT2AADORA3CCNE2 | |
| SCHEMBL7436632 | 0.81 | PDE2A (0.53) | PDE2AKMT2AKDM4EALDH1A1ADORA3 | |
| SCHEMBL6051979 | 0.80 | PDE2A (0.53) | PDE2AADORA3RXFP1CCNE2CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861396-A | CARDIOVASCULAR DISORDERS AND UROGENITAL SYSTEMS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-01-19 | — | — | US | disclosed |
| EP-0771799-A1 | Purin-6-one derivatives | BAYER AG (DE) | 1997-05-07 | — | — | EP | disclosed |