Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.35 |
| ▸ | CHRNG | P07510 | 1/20 | 0.35 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442583 | 1.00 | L3MBTL1 (0.37) | L3MBTL1ATMALDH1A1MAPK1CA1 | |
| SCHEMBL7439116 | 0.87 | ALDH1A1 (0.40) | L3MBTL1ALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL7444252 | 0.87 | ALDH1A1 (0.40) | L3MBTL1ALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL9240911 | 0.82 | F10 (0.44) | L3MBTL1ATMALDH1A1MAPK1CA1 | |
| SCHEMBL8014005 | 0.70 | CA1 (0.46) | L3MBTL1ATMALDH1A1MAPK1CA1 | |
| SCHEMBL14966602 | 0.70 | MEN1 (0.42) | L3MBTL1ATMALDH1A1MAPK1POLB | |
| SCHEMBL837139 | 0.68 | ALDH1A1 (0.55) | L3MBTL1ATMALDH1A1MAPK1CA1 | |
| SCHEMBL14967672 | 0.68 | ALDH1A1 (0.43) | L3MBTL1ALDH1A1MAPK1POLBKMT2A | |
| SCHEMBL14967628 | 0.68 | NPC1 (0.45) | L3MBTL1ALDH1A1KMT2AMEN1CYP3A4 | |
| SCHEMBL14967054 | 0.68 | BACE1 (0.41) | L3MBTL1ATMALDH1A1MAPK1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6180785-B1 | REFLUXING AMINOTHIOPHENOL OR AMINOTHIONAPHTHOL WITH ALKOXYPHENYL-4-CARBOALKOXY-1,3,2-DIOXATHIOLANE | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2001-01-30 | — | — | US | disclosed |
| US-5869697-A | Process for preparing diltiazem | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 1999-02-09 | — | — | US | disclosed |