Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 5/20 | 0.44 |
| ▸ | HTR2C | P28335 | 4/20 | 0.44 |
| ▸ | DRD1 | P21728 | 3/20 | 0.44 |
| ▸ | HRH1 | P35367 | 3/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.44 |
| ▸ | HTR2B | P41595 | 3/20 | 0.44 |
| ▸ | HTR7 | P34969 | 3/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | HRH2 | P25021 | 2/20 | 0.44 |
| ▸ | HTR1D | P28221 | 2/20 | 0.44 |
| ▸ | HTR1B | P28222 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | DRD5 | P21918 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HTR5A | P47898 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7443381 | 0.93 | DRD2 (0.44) | KCNH2TMEM97SIGMAR1DRD2HTR2C | |
| SCHEMBL7448170 | 0.87 | DRD1 (0.41) | KCNH2TMEM97SIGMAR1DRD2HTR2C | |
| SCHEMBL7441589 | 0.86 | KDM4E (0.41) | KCNH2SIGMAR1DRD2HTR2CDRD1 | |
| SCHEMBL10461677 | 0.86 | KDM4E (0.49) | KCNH2TMEM97DRD2HTR2CDRD1 | |
| SCHEMBL7436648 | 0.85 | KCNH2 (0.48) | KCNH2TMEM97SIGMAR1DRD2HTR2C | |
| SCHEMBL10460769 | 0.85 | ABCB11 (0.56) | KCNH2SIGMAR1DRD2HTR2CDRD1 | |
| SCHEMBL7441777 | 0.84 | KCNH2 (0.48) | KCNH2SIGMAR1DRD2HTR2CDRD1 | |
| SCHEMBL7446532 | 0.83 | ABCB11 (0.47) | KCNH2SIGMAR1DRD2HTR2CDRD1 | |
| Oxalic Acid SCHEMBL10461465 | 0.83 | ABCB11 (0.54) | KCNH2SIGMAR1DRD2HTR2CDRD1 | |
| Oxalic Acid SCHEMBL10460714 | 0.82 | KDM4E (0.53) | KCNH2SIGMAR1DRD2HTR2CDRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5070087-A | Aryl(alkyland alkylene)-N-((phenoxy and phenylthio)alkyl) aminoheterocyclics as cardiovascular, anthihistaminic, antisecretory and antiallergy agents | A. H. ROBINS COMPANY, INCORPORATED (US) | 1991-12-03 | — | — | US | disclosed |