Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 11/20 | 0.48 |
| ▸ | PDE5A | O76074 | 2/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.45 |
| ▸ | CDK9 | P50750 | 2/20 | 0.45 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.43 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29269603 | 0.74 | ALDH1A1 (0.51) | CCNT1CDK9CCNB2CDK1CCNB1 | |
| SCHEMBL858602 | 0.73 | BRD4 (0.62) | AURKACCNT1CDK9CCNB2CDK1 | |
| SCHEMBL4768889 | 0.72 | NUDT1 (0.58) | FYNCCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL16052809 | 0.71 | CCNT1 (0.61) | CCNT1CDK9CCNB2CDK1CCNB1 | |
| SCHEMBL5990466 | 0.70 | METAP2 (0.49) | HSD17B10GAA | |
| SCHEMBL301996 | 0.70 | CA1 (0.71) | HSD17B10GAAMAPT | |
| SCHEMBL29788337 | 0.70 | CA1 (0.71) | HSD17B10GAAMAPT | |
| SCHEMBL29429633 | 0.70 | CA1 (0.71) | HSD17B10GAAMAPT | |
| SCHEMBL11626993 | 0.69 | ALDH1A1 (0.53) | HSD17B10GAA | |
| SCHEMBL13506615 | 0.68 | SRC (0.47) | FYNCCNB2CDK1CCNB1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002062795-A9 | DIHYDROPYRAZOLOPYRIDINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | MITSUBISHI PHARMA CORP (JP) | 2002-10-10 | — | — | WO | disclosed |