Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.58 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.47 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.47 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.47 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 5/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.40 |
| ▸ | CDK2 | P24941 | 5/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 4/20 | 0.40 |
| ▸ | CDK1 | P06493 | 4/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 4/20 | 0.40 |
| ▸ | FYN | P06241 | 2/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | CCND2 | P30279 | 1/20 | 0.37 |
| ▸ | CCND3 | P30281 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4762978 | 0.84 | BCAT2 (0.44) | NUDT1CSNK1A1TYRO3DYRK1BBCAT2 | |
| SCHEMBL1694890 | 0.81 | KDM4E (0.45) | NUDT1CSNK1A1TYRO3DYRK1BCCNE2 | |
| SCHEMBL27872261 | 0.80 | NUDT1 (0.59) | NUDT1CSNK1A1TYRO3DYRK1BBCAT2 | |
| SCHEMBL4770923 | 0.78 | CDC7 (0.38) | NUDT1CSNK1A1TYRO3DYRK1BCCNE2 | |
| SCHEMBL4768901 | 0.75 | NUDT1 (0.65) | NUDT1CSNK1A1TYRO3DYRK1BBCAT2 | |
| SCHEMBL27991327 | 0.75 | NUDT1 (0.61) | NUDT1CSNK1A1TYRO3DYRK1BBCAT2 | |
| SCHEMBL4772891 | 0.73 | NUDT1 (1.00) | NUDT1CSNK1A1TYRO3DYRK1B | |
| SCHEMBL7443909 | 0.72 | FYN (0.48) | CCNB2CDK1CCNB1CCNB3FYN | |
| SCHEMBL27636994 | 0.72 | BCAT2 (0.47) | NUDT1CSNK1A1TYRO3DYRK1BBCAT2 | |
| SCHEMBL28757944 | 0.71 | KDM4E (0.47) | NUDT1CSNK1A1TYRO3DYRK1BBCAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1934181-A2 | KINASE INHIBITORS | Devgen NV (BE) | 2008-06-25 | — | — | EP | claimed |
| WO-2007042321-A2 | KINASE INHIBITORS | DEVGEN N.V. (BE) | 2007-04-19 | — | — | WO | claimed |