Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | KMO | O15229 | 2/20 | 0.45 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1549312 | 0.81 | KDM1A (0.56) | CTSSKMOKDM1AXDHIDO1 | |
| SCHEMBL1416671 | 0.79 | CTSS (0.54) | CTSSKMOKDM1AXDHIDO1 | |
| SCHEMBL29746381 | 0.79 | CTSS (0.54) | CTSSKMOKDM1AXDHIDO1 | |
| SCHEMBL3751766 | 0.78 | KDM1A (0.56) | CTSSKMOKDM1AXDHIDO1 | |
| SCHEMBL12427721 | 0.78 | KDM1A (0.45) | CTSSKMOKDM1AXDHIDO1 | |
| SCHEMBL4592102 | 0.78 | ALDH1A1 (0.58) | CTSSKMOKDM1AXDHIDO1 | |
| SCHEMBL6856540 | 0.77 | CTSS (0.52) | CTSSKMOKDM1AXDHIDO1 | |
| SCHEMBL19737563 | 0.75 | TTK (0.49) | ALDH1A1MAOBCYP1A2CYP3A4KMT2A | |
| SCHEMBL2304614 | 0.75 | CTSS (0.56) | CTSSKMOKDM1AXDHIDO1 | |
| SCHEMBL26613402 | 0.74 | BACE1 (0.56) | KDM4EMAOBBACE1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691966-A1 | QUINOLINES AS TYPE IV PHOSPHODIESTERASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1996-01-17 | — | — | EP | disclosed |
| WO-1994022852-A1 | QUINOLINES AS TYPE IV PHOSPHODIESTERASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1994-10-13 | — | — | WO | disclosed |