Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 11/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MLYCD | O95822 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7445267 | 0.87 | MLYCD (0.55) | LMNAMLYCDHTTMEN1KMT2A | |
| SCHEMBL27627257 | 0.75 | CHRNA7 (0.57) | TBXAS1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9555055 | 0.75 | ALDH1A1 (0.50) | LMNATSHRHTTMEN1KMT2A | |
| SCHEMBL4068054 | 0.75 | KMT2A (0.72) | LMNATBXAS1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11272120 | 0.74 | ALDH1A1 (0.49) | LMNATSHRMLYCDHTTMEN1 | |
| Hydrochloric Acid SCHEMBL27658720 | 0.74 | TBXAS1 (0.56) | TBXAS1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8922653 | 0.73 | ALDH1A1 (0.54) | LMNATSHRMLYCDKDM4EHTT | |
| SCHEMBL7769274 | 0.73 | HTT (0.44) | LMNATBXAS1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6297866 | 0.72 | TBXAS1 (0.55) | TBXAS1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9475090 | 0.72 | PLOD2 (0.60) | LMNATBXAS1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0817795-B1 | NOVEL 4-SUBSTITUTED-3-PEPTIDYL-AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE INHIBITOR | NAEJA PHARMACEUTICAL INC (CA) | 2000-11-15 | — | — | EP | disclosed |
| US-5986108-A | ENZYME INHIBITORS | SYNPHAR LABORATORIES, INC. (CA) | 1999-11-16 | — | — | US | disclosed |
| EP-0817795-A1 | NOVEL 4-SUBSTITUTED-3-PEPTIDYL-AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE INHIBITOR | SYNPHAR LABORATORIES INC. (CA) | 1998-01-14 | — | — | EP | disclosed |
| WO-1996032408-A1 | NOVEL 4-SUBSTITUTED-3-PEPTIDYL-AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE INHIBITOR | SYNPHAR LABORATORIES, INC. (US) | 1996-10-17 | — | — | WO | disclosed |