Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 9/20 | 0.41 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | YARS1 | P54577 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7444999 | 0.84 | OPRD1 (0.49) | OPRD1CASP1 | |
| SCHEMBL30843955 | 0.81 | OPRD1 (0.46) | OPRD1OPRM1OPRK1 | |
| SCHEMBL29531463 | 0.81 | OPRD1 (0.46) | OPRD1OPRM1OPRK1 | |
| SCHEMBL4434143 | 0.80 | SLC7A5 (0.48) | OPRD1OPRM1YARS1 | |
| SCHEMBL4434130 | 0.80 | SLC7A5 (0.48) | OPRD1OPRM1YARS1 | |
| SCHEMBL23598458 | 0.80 | SLC7A5 (0.48) | OPRD1OPRM1YARS1 | |
| SCHEMBL9665005 | 0.80 | SLC7A5 (0.48) | OPRD1OPRM1YARS1 | |
| SCHEMBL9664998 | 0.80 | SLC7A5 (0.48) | OPRD1OPRM1YARS1 | |
| SCHEMBL31020880 | 0.80 | NPY1R (0.49) | OPRD1RENOPRM1 | |
| Hydrochloric Acid SCHEMBL20335514 | 0.80 | SLC7A5 (0.47) | OPRD1OPRM1YARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519748-A2 | Peptidyl derivatives as inhibitors of interleukin-1B converting enzyme | MERCK & CO. INC. (US) | 1992-12-23 | — | — | EP | claimed |