Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 4/20 | 0.49 |
| ▸ | CASP1 | P29466 | 3/20 | 0.49 |
| ▸ | CASP3 | P42574 | 8/20 | 0.47 |
| ▸ | CASP7 | P55210 | 5/20 | 0.47 |
| ▸ | CASP9 | P55211 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29381722 | 0.84 | AGTR2 (0.50) | OPRD1CASP3CASP7 | |
| SCHEMBL7445005 | 0.84 | OPRD1 (0.41) | OPRD1CASP1 | |
| SCHEMBL5686640 | 0.83 | OPRD1 (0.43) | OPRD1CASP1CASP3CASP7CASP9 | |
| SCHEMBL30843955 | 0.83 | OPRD1 (0.46) | OPRD1 | |
| SCHEMBL29531463 | 0.83 | OPRD1 (0.46) | OPRD1 | |
| SCHEMBL6687472 | 0.82 | CASP1 (0.46) | CASP1CASP3CASP7CASP9 | |
| SCHEMBL31020880 | 0.82 | NPY1R (0.49) | OPRD1 | |
| SCHEMBL29946109 | 0.82 | CASP1 (0.61) | OPRD1CASP1CASP3CASP7 | |
| SCHEMBL5686633 | 0.82 | CASP1 (0.49) | OPRD1CASP1CASP3CASP7CASP9 | |
| SCHEMBL31199054 | 0.81 | OPRD1 (0.44) | OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519748-A2 | Peptidyl derivatives as inhibitors of interleukin-1B converting enzyme | MERCK & CO. INC. (US) | 1992-12-23 | — | — | EP | claimed |