Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | SLC6A15 | Q9H2J7 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 13/20 | 0.33 |
| ▸ | CTSL | P07711 | 13/20 | 0.33 |
| ▸ | CTSS | P25774 | 9/20 | 0.33 |
| ▸ | CTSB | P07858 | 3/20 | 0.33 |
| ▸ | CTSV | O60911 | 2/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7445866 | 0.83 | CTSK (0.47) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7453952 | 0.81 | CTSK (0.40) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL7453958 | 0.80 | CTSK (0.54) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL7450638 | 0.80 | CTSK (0.39) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL7450642 | 0.80 | TRPV4 (0.47) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL7514439 | 0.78 | CTSK (0.43) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4041763 | 0.70 | CTSK (0.45) | DPP4DPP8DPP9DPP7CTSK | |
| SCHEMBL7445825 | 0.69 | CTSK (0.42) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL7508575 | 0.68 | CTSK (0.47) | CTSKCTSLCTSSCTSBKDM4E | |
| SCHEMBL7449697 | 0.68 | CTSK (0.42) | CTSKCTSLCTSSCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002533452-A | — | — | 2002-10-08 | — | — | JP | claimed |
| EP-1140897-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2002-04-03 | — | — | EP | claimed |
| EP-1140897-A1 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2001-10-10 | — | — | EP | claimed |
| WO-2000039115-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-07-06 | — | — | WO | claimed |
| EP-1140897-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2002-04-03 | — | — | EP | disclosed |
| EP-1140897-A1 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039115-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-07-06 | — | — | WO | disclosed |