Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 12/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7495730 | 0.90 | CA2 (0.36) | FFAR1CYP2C9CYP2B6SLCO1B3CA2 | |
| SCHEMBL7434312 | 0.90 | MAPT (0.38) | GAANPSR1ALDH1A1ADRA1DADRA1A | |
| SCHEMBL10994839 | 0.85 | FFAR1 (0.35) | FFAR1CYP2C9CYP2B6SLCO1B3HCRTR2 | |
| SCHEMBL7437018 | 0.85 | TSHR (0.32) | FFAR1CA2GAAHTTNPSR1 | |
| SCHEMBL7435907 | 0.85 | KDM4E (0.40) | GAANPSR1ALDH1A1ADRA1DADRA1A | |
| SCHEMBL7429561 | 0.84 | CA2 (0.37) | FFAR1CYP2C9CYP2B6SLCO1B3CA2 | |
| SCHEMBL7437936 | 0.84 | CA2 (0.34) | FFAR1CA2MCHR1HTR1ADRD2 | |
| SCHEMBL7430526 | 0.83 | SPHK1 (0.30) | — | |
| SCHEMBL7440714 | 0.83 | MAPT (0.37) | GAANPSR1ALDH1A1ADRA1DADRA1A | |
| SCHEMBL7437126 | 0.82 | MCHR1 (0.35) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |