Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 9/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10989700 | 0.87 | CHRM2 (0.33) | MCHR1POLBLMNATP53NPC1 | |
| SCHEMBL7430526 | 0.84 | SPHK1 (0.30) | — | |
| SCHEMBL7428117 | 0.84 | LMNA (0.43) | MCHR1LMNANPC1CHRM2CHRM1 | |
| SCHEMBL7434312 | 0.84 | MAPT (0.38) | POLBLMNANPC1KMT2A | |
| SCHEMBL7437133 | 0.82 | ALDH1A1 (0.44) | MCHR1POLBLMNATP53KMT2A | |
| SCHEMBL7431674 | 0.82 | LMNA (0.42) | LMNANPC1CHRM2CHRM1KMT2A | |
| SCHEMBL7446161 | 0.82 | FFAR1 (0.34) | MCHR1 | |
| SCHEMBL7434217 | 0.81 | ADRB3 (0.38) | MCHR1LMNANPC1 | |
| SCHEMBL7439160 | 0.80 | NPC1 (0.42) | LMNATP53NPC1 | |
| SCHEMBL7446102 | 0.80 | LMNA (0.39) | MCHR1LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |