Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440714 | 0.91 | MAPT (0.37) | TSHRALDH1A1NPC1POLBGAA | |
| SCHEMBL7436565 | 0.86 | ALDH1A1 (0.39) | TSHRALDH1A1NPSR1 | |
| SCHEMBL10997571 | 0.86 | FFAR1 (0.34) | ALDH1A1FFAR1CA2RAB9A | |
| SCHEMBL7446161 | 0.85 | FFAR1 (0.34) | ALDH1A1FFAR1CA2HTTGAA | |
| SCHEMBL7443120 | 0.84 | LMNA (0.41) | TSHRALDH1A1NPC1RAB9AHTT | |
| SCHEMBL7436237 | 0.84 | TEAD1 (0.42) | POLB | |
| SCHEMBL7439952 | 0.83 | CA2 (0.38) | TSHRALDH1A1FFAR1CA2POLB | |
| SCHEMBL7445139 | 0.83 | MAPT (0.35) | ALDH1A1NPC1NPSR1 | |
| SCHEMBL7434312 | 0.82 | MAPT (0.38) | TSHRALDH1A1NPC1POLBGAA | |
| SCHEMBL7437024 | 0.81 | LMNA (0.45) | ALDH1A1NPC1RAB9APOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |