Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | FPR1 | P21462 | 3/20 | 0.34 |
| ▸ | FPR2 | P25090 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.32 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6759870 | 0.92 | FFAR1 (0.36) | FFAR1CASP1FPR1FPR2ALDH1A1 | |
| SCHEMBL4436745 | 0.87 | SMN1; SMN2 (0.41) | CASP1SMN1; SMN2FPR1ALDH1A1LMNA | |
| SCHEMBL4436753 | 0.87 | FPR1 (0.42) | FFAR1CASP1SMN1; SMN2FPR1FPR2 | |
| SCHEMBL4436912 | 0.85 | SMN1; SMN2 (0.40) | CASP1SMN1; SMN2FPR1ALDH1A1PTGES | |
| SCHEMBL4426298 | 0.84 | CASP1 (0.37) | FFAR1CASP1FPR1CTSA | |
| SCHEMBL4426779 | 0.84 | FPR1 (0.37) | FFAR1CASP1SMN1; SMN2FPR1FPR2 | |
| SCHEMBL4429245 | 0.83 | CTSA (0.37) | FFAR1CASP1FPR1ALDH1A1PTGES | |
| SCHEMBL4426944 | 0.82 | FPR1 (0.39) | CASP1SMN1; SMN2FPR1FPR2PPARG | |
| SCHEMBL4426307 | 0.82 | CASP1 (0.39) | CASP1SMN1; SMN2FPR1ALDH1A1 | |
| SCHEMBL4429149 | 0.82 | CYP26A1 (0.39) | CASP1FPR1CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1213288-A1 | Propanoic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-06-12 | — | — | EP | claimed |