Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | FPR1 | P21462 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | GPR88 | Q9GZN0 | 3/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4436912 | 0.98 | SMN1; SMN2 (0.40) | SMN1; SMN2CASP1FPR1ALDH1A1PTGES | |
| SCHEMBL4426307 | 0.95 | CASP1 (0.39) | SMN1; SMN2CASP1FPR1ALDH1A1 | |
| SCHEMBL4436753 | 0.93 | FPR1 (0.42) | SMN1; SMN2CASP1FPR1ALDH1A1PTGES | |
| SCHEMBL4434290 | 0.92 | FPR1 (0.39) | SMN1; SMN2CASP1FPR1GPR88 | |
| SCHEMBL4427187 | 0.90 | MMP2 (0.38) | SMN1; SMN2CASP1FPR1 | |
| SCHEMBL7429087 | 0.90 | MMP2 (0.38) | SMN1; SMN2CASP1FPR1 | |
| SCHEMBL4427933 | 0.90 | ITGB3 (0.42) | CASP1FPR1 | |
| SCHEMBL4435231 | 0.89 | CASP1 (0.38) | CASP1FPR1PPARG | |
| SCHEMBL7431479 | 0.89 | CASP1 (0.38) | CASP1FPR1PPARG | |
| SCHEMBL4429239 | 0.89 | CASP1 (0.38) | CASP1FPR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1213288-B1 | Propanoic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2009-01-14 | — | — | EP | disclosed |
| EP-1213288-A1 | Propanoic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-06-12 | — | — | EP | disclosed |