Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 4/20 | 0.39 |
| ▸ | FPR1 | P21462 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4436912 | 0.95 | SMN1; SMN2 (0.40) | CASP1FPR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4436745 | 0.95 | SMN1; SMN2 (0.41) | CASP1FPR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4434290 | 0.92 | FPR1 (0.39) | CASP1FPR1SMN1; SMN2KMT2A | |
| SCHEMBL4427187 | 0.91 | MMP2 (0.38) | CASP1FPR1SMN1; SMN2 | |
| SCHEMBL7429087 | 0.91 | MMP2 (0.38) | CASP1FPR1SMN1; SMN2 | |
| SCHEMBL4427933 | 0.91 | ITGB3 (0.42) | CASP1FPR1 | |
| SCHEMBL4429245 | 0.90 | CTSA (0.37) | CASP1FPR1ALDH1A1CNR1CNR2 | |
| SCHEMBL4429239 | 0.90 | CASP1 (0.38) | CASP1FPR1 | |
| SCHEMBL4435231 | 0.90 | CASP1 (0.38) | CASP1FPR1 | |
| SCHEMBL7431479 | 0.90 | CASP1 (0.38) | CASP1FPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1213288-B1 | Propanoic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2009-01-14 | — | — | EP | disclosed |
| EP-1213288-A1 | Propanoic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-06-12 | — | — | EP | disclosed |