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SCHEMBL7446522

SCHEMBL7446522

C[C@@H](C(=O)O)N1CC(=O)N(C(CS)Cc2ccccc2)C1=O

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ CPA3 P15088 1/20 0.44
▸ FOLH1 Q04609 1/20 0.44
▸ ALDH1A1 P00352 1/20 0.43
▸ PKM P14618 1/20 0.43
▸ MME P08473 5/20 0.42
▸ SLC1A2 P43004 1/20 0.39
▸ ALOX15 P16050 1/20 0.38
▸ MAPT P10636 1/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7437103 0.88 MME (0.43) CPA3FOLH1ALDH1A1PKMMME
SCHEMBL7435392 0.88 MME (0.43) CPA3FOLH1ALDH1A1PKMMME
SCHEMBL7442303 0.86 ALDH1A1 (0.53) CPA3FOLH1ALDH1A1PKMALOX15
SCHEMBL7439151 0.86 MME (0.46) CPA3FOLH1ALDH1A1PKMMME
SCHEMBL7432083 0.85 ACE (0.44) CPA3FOLH1ALDH1A1PKMMME
SCHEMBL7435805 0.84 CPA3 (0.38) CPA3FOLH1ALDH1A1PKMMME
SCHEMBL7431966 0.82 MEN1 (0.41) CPA3FOLH1ALDH1A1PKMMME
SCHEMBL7426791 0.81 CPA3 (0.38) CPA3FOLH1ALDH1A1PKMMME
SCHEMBL7440464 0.78 FOLH1 (0.41) CPA3FOLH1ALDH1A1PKMMME
SCHEMBL7446529 0.78 ACE (0.41) ALDH1A1PKMSLC1A2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0640594-A1 Hydantoin derivative as metalloprotease inhibitor FUJIREBIO INC. (JP) 1995-03-01 — — EP disclosed