Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 4/20 | 0.43 |
| ▸ | CPA3 | P15088 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442303 | 0.90 | ALDH1A1 (0.53) | ALDH1A1PKMCPA3FOLH1ALOX15 | |
| SCHEMBL7446522 | 0.86 | CPA3 (0.44) | MMEALDH1A1PKMCPA3FOLH1 | |
| SCHEMBL7437103 | 0.84 | MME (0.43) | MMEALDH1A1PKMCPA3FOLH1 | |
| SCHEMBL7435392 | 0.84 | MME (0.43) | MMEALDH1A1PKMCPA3FOLH1 | |
| SCHEMBL7432083 | 0.81 | ACE (0.44) | MMEALDH1A1PKMACECPA3 | |
| SCHEMBL7439156 | 0.80 | MME (0.44) | MMEALDH1A1PKMACE | |
| SCHEMBL7435805 | 0.80 | CPA3 (0.38) | MMEALDH1A1PKMACECPA3 | |
| SCHEMBL7431966 | 0.78 | MEN1 (0.41) | MMEALDH1A1PKMCPA3FOLH1 | |
| SCHEMBL7433437 | 0.78 | DNMT1 (0.57) | PKMMAPTSMN1; SMN2GAA | |
| SCHEMBL7426791 | 0.77 | CPA3 (0.38) | MMEALDH1A1PKMCPA3FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |