Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766644 | 0.89 | HAO1 (0.43) | TNFKMT2AMEN1SMN1; SMN2RAB9A | |
| SCHEMBL5738593 | 0.82 | SMN1; SMN2 (0.62) | KMT2AMEN1SMN1; SMN2RAB9AHTT | |
| SCHEMBL24634980 | 0.79 | PKM (0.56) | KMT2AMEN1SMN1; SMN2RAB9AHTT | |
| SCHEMBL5739537 | 0.76 | RAB9A (0.69) | KMT2AMEN1SMN1; SMN2RAB9AHTT | |
| SCHEMBL5739984 | 0.76 | RAB9A (0.69) | KMT2ASMN1; SMN2RAB9AHTTMAPT | |
| SCHEMBL5738542 | 0.76 | ALDH1A1 (0.54) | KMT2AMEN1SMN1; SMN2RAB9AHTT | |
| SCHEMBL10418997 | 0.75 | HTT (0.63) | KMT2AMEN1SMN1; SMN2RAB9AHTT | |
| SCHEMBL12554864 | 0.71 | TSHR (0.56) | KMT2ASMN1; SMN2HTTTSHRL3MBTL1 | |
| SCHEMBL16563423 | 0.69 | TRPV1 (0.48) | SMN1; SMN2RAB9AHTTMAPTTSHR | |
| SCHEMBL596327 | 0.69 | TSHR (0.58) | KMT2ASMN1; SMN2HTTTSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005664-A1 | 6,7,8,9-TETRAHYDRO-5H-IMIDAZO[1,2-a]AZEPINE-3-ACETIC ACID DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL USE THEREOF | SYNTHELABO (FR) | 1998-02-12 | — | — | WO | disclosed |