Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CDC25B | P30305 | 1/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10140601 | 1.00 | SLC15A1 (0.62) | SLC15A1ALDH1A1MAPK1L3MBTL1CDC25B | |
| SCHEMBL1264374 | 0.87 | SLC15A1 (0.61) | SLC15A1ALDH1A1MAPK1L3MBTL1CDC25B | |
| SCHEMBL32681189 | 0.87 | SLC15A1 (0.61) | SLC15A1ALDH1A1MAPK1L3MBTL1CDC25B | |
| SCHEMBL589203 | 0.87 | SLC15A1 (0.61) | SLC15A1ALDH1A1MAPK1L3MBTL1CDC25B | |
| SCHEMBL730848 | 0.87 | SLC15A1 (0.65) | SLC15A1ALDH1A1MAPK1L3MBTL1ALPI | |
| SCHEMBL4523936 | 0.87 | SLC15A1 (0.65) | SLC15A1ALDH1A1MAPK1L3MBTL1ALPI | |
| SCHEMBL5898461 | 0.87 | SLC15A1 (0.65) | SLC15A1ALDH1A1MAPK1L3MBTL1ALPI | |
| SCHEMBL589202 | 0.87 | SLC15A1 (0.61) | SLC15A1ALDH1A1MAPK1L3MBTL1CDC25B | |
| SCHEMBL8249778 | 0.86 | SLC15A1 (0.57) | SLC15A1ALDH1A1MAPK1L3MBTL1CDC25B | |
| SCHEMBL7470329 | 0.86 | SLC15A1 (0.57) | SLC15A1ALDH1A1MAPK1L3MBTL1CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9439986-B2 | Tricarbonyl technetium-99m, rhenium-185/187, or rhenium-188 labeled cyclic RGD derivatives and uses thereof | BIO IMAGING KOREA CO., LTD. (KR) | 2016-09-13 | — | — | US | disclosed |
| US-20130064766-A1 | TRICARBONYL TECHNETIUM-99m OR RHENIUM-188 LABELED CYCLIC RGD DERIVATIVES, A PREPARATION METHOD THEREOF, AND A PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVES AS AN ACTIVE INGREDIENT FOR USE IN THE DIAGNOSIS OR TREATMENT OF ANGIOGENESIS-RELATED DISEASES | SNU R&DB FOUNDATION (KR) | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130064766-A1 | TRICARBONYL TECHNETIUM-99m OR RHENIUM-188 LABELED CYCLIC RGD DERIVATIVES, A PREPARATION METHOD THEREOF, AND A PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVES AS AN ACTIVE INGREDIENT FOR USE IN THE DIAGNOSIS OR TREATMENT OF ANGIOGENESIS-RELATED DISEASES | ITGAV, ITGA5, KDR | SLC15A1 1976/4885ALDH1A1 4074/4885MAPK1 2911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.