Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.46 |
| ▸ | ITGAV | P06756 | 5/20 | 0.42 |
| ▸ | ENO1 | P06733 | 1/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7369685 | 0.90 | ITGB3 (0.47) | ITGB3ITGA2BITGAVFKBP1AOPRM1 | |
| Hydrochloric Acid SCHEMBL7370233 | 0.89 | ITGB3 (0.47) | ITGB3ITGA2BITGAVFKBP1AOPRM1 | |
| SCHEMBL7338126 | 0.86 | ITGB3 (0.52) | ITGB3ITGA2BITGAVSLC1A2KCNA5 | |
| Hydrochloric Acid SCHEMBL7338692 | 0.85 | ITGB3 (0.51) | ITGB3ITGA2BITGAVSLC1A2KCNA5 | |
| SCHEMBL7342847 | 0.83 | ITGB3 (0.44) | ITGB3ITGA2BITGAVENO1FKBP1A | |
| SCHEMBL8618344 | 0.81 | ITGB3 (0.35) | ITGB3ITGA2BITGAVENO1FKBP1A | |
| SCHEMBL8617240 | 0.80 | ITGB3 (0.39) | ITGB3ITGA2BITGAVFKBP1AOPRM1 | |
| SCHEMBL7365261 | 0.78 | ITGB3 (0.47) | ITGB3ITGA2BITGAVFKBP1AOPRM1 | |
| SCHEMBL7345393 | 0.72 | ITGB3 (0.46) | ITGB3ITGA2BITGAVFKBP1A | |
| SCHEMBL8621139 | 0.69 | ITGB3 (0.37) | ITGB3ITGA2BITGAVSLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0866705-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 1999-03-03 | — | — | EP | disclosed |
| EP-0866705-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1998-09-30 | — | — | EP | disclosed |
| WO-1997014417-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1997-04-24 | — | — | WO | disclosed |